Global roles of Ste11p, cell type, and pheromone in the control of gene expression during early sexual differentiation in fission yeast.

Abstract excerpt

Fission yeast cells belong to one of two specialized cell types, M or P. Specific environmental conditions trigger sexual differentiation, which leads to an internal program starting with pheromone signaling between M and P cells, followed by mating, meiosis, and sporulation. The initial steps of this process are controlled by Ste11p, a master transcriptional regulator that activates the expression of cell...

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