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Article

The Polycomb group protein Ring1b is essential for pectoral fin development.

Development (Cambridge, England) - 1 Jun 2012

van der Velden Yme U, Wang Liqin, van Lohuizen Maarten, Haramis Anna-Pavlina G

Abstract excerpt

Polycomb group (PcG) proteins are transcriptional repressors that mediate epigenetic gene silencing by chromatin modification. PcG-mediated gene repression is implicated in development, cell differentiation, stem-cell fate maintenance and cancer. However, analysis of the roles of PcG proteins in orchestrating vertebrate developmental programs in vivo has been hampered by the early embryonic lethality of several...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22619390
DOI: 10.1242/dev.077156

Genes

FGF4
PRC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The Polycomb group protein Ring1b is essential for pectoral fin development.PMID 22619390Read ↗

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