Nucleotide substitutions revealing specific functions of Polycomb group genes.

doi:10.1016/j.ymgme.2015.01.007

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Article

Nucleotide substitutions revealing specific functions of Polycomb group genes.

Molecular genetics and metabolism - 1 Apr 2015

Bajusz Izabella, Sipos László, Pirity Melinda K

Abstract excerpt

POLYCOMB group (PCG) proteins belong to the family of epigenetic regulators of genes playing important roles in differentiation and development. Mutants of PcG genes were isolated first in the fruit fly, Drosophila melanogaster, resulting in spectacular segmental transformations due to the ectopic expression of homeotic genes. Homologs of Drosophila PcG genes were also identified in plants and in vertebrates and...

Topics

Alleles
Animals
Cell Differentiation
Chromatin
Drosophila Proteins
Drosophila melanogaster
Epigenesis, Genetic
Gene Expression Regulation
Genes, Homeobox
Mice
Nucleotides
Point Mutation
Polycomb-Group Proteins

Source

Open in PubMed

Identifiers

PMID: 25669595
DOI: 10.1016/j.ymgme.2015.01.007

Genes

PRC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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