Article
Polycomblike-2-deficient mice exhibit normal left-right asymmetry.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Mar 2007
Wang Shusheng, He Fenglei, Xiong Wei, Gu Shuping, Liu Hongbin, Zhang Tao, Yu Xueyan, Chen Yiping
Abstract excerpt
Polycomb group (PcG) proteins are required for maintaining the repressed state of developmentally important genes such as homeotic genes. Polycomblike (Pcl), a member of PcG genes with two characteristic PHD finger motifs, was shown to strongly enhance the effects of PcG genes in Drosophila. Three Pcl genes exist in the mouse genome, with their function largely unknown. Our previous studies demonstrate that the...
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