Functional analysis of mouse Polycomb group genes.

doi:10.1007/s000180050126

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Article

Functional analysis of mouse Polycomb group genes.

Cellular and molecular life sciences : CMLS - 1 Jan 1998

van Lohuizen M

Abstract excerpt

Two groups of genes, the Polycomb group (Pc-G) and trithorax group (trx-G), have been identified in Drosophila to provide a transcriptional memory mechanism. They ensure the maintenance of transcription patterns of key regulators such as the Hox genes and thereby the correct execution of developm...

Topics

Animals
DNA-Binding Proteins
Drosophila
Drosophila Proteins
Genes, Homeobox
Insect Proteins
Mice
Multigene Family
Phenotype
Polycomb Repressive Complex 1
Sequence Homology, Nucleic Acid
Transcription Factors

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