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Article

The polycomb group protein ring1b/rnf2 is specifically required for craniofacial development.

PloS one - 1 Jan 2013

van der Velden Yme U, Wang Liqin, Querol Cano Laia, Haramis Anna-Pavlina G

Abstract excerpt

Polycomb group (PcG) genes are chromatin modifiers that mediate epigenetic silencing of target genes. PcG-mediated epigenetic silencing is implicated in embryonic development, stem cell plasticity, cell fate maintenance, cellular differentiation and cancer. However, analysis of the roles of PcG proteins in maintaining differentiation programs during vertebrate embryogenesis has been hampered due to the early...

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Body Patterning
Chondrocytes
Chondrogenesis
Jaw
Muscles
Neural Crest

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Zebrafish Proteins

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PMID: 24040141
DOI: 10.1371/journal.pone.0073997
PMCID: PMC3770662

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