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Article

No effect of the transforming growth factor β1 promoter polymorphism C-509T on TGFB1 gene expression, protein secretion, or cellular radiosensitivity.

International journal of radiation oncology, biology, physics - 1 Feb 2013

Reuther Sebastian, Metzke Elisabeth, Bonin Michael, Petersen Cordula, Dikomey Ekkehard, Raabe Annette

Abstract excerpt

PURPOSE: To study whether the promoter polymorphism (C-509T) affects transforming growth factor β1 gene (TGFB1) expression, protein secretion, and/or cellular radiosensitivity for both human lymphocytes and fibroblasts. METHODS AND MATERIALS: Experiments were performed with lymphocytes taken either from 124 breast cancer patients or 59 pairs of normal monozygotic twins. We used 15 normal human primary fibroblast...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22592044
DOI: 10.1016/j.ijrobp.2012.01.090

Genes

TGFB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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