Individual patient data meta-analysis shows no association between the SNP rs1800469 in TGFB and late radiotherapy toxicity.

doi:10.1016/j.radonc.2012.10.017

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Article

Individual patient data meta-analysis shows no association between the SNP rs1800469 in TGFB and late radiotherapy toxicity.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology - 1 Dec 2012

Barnett Gillian C, Elliott Rebecca M, Alsner Jan, Andreassen Christian N, Abdelhay Osama, Burnet Neil G, Chang-Claude Jenny, Coles Charlotte E, Gutiérrez-Enríquez Sara, Fuentes-Raspall Maria J, Alonso-Muñoz Maria C, Kerns Sarah, Raabe Annette, Symonds R Paul, Seibold Petra, Talbot Chris J, Wenz Frederik, Wilkinson Jennifer, Yarnold John, Dunning Alison M, Rosenstein Barry S, West Catharine M L, Bentzen Søren M

Abstract excerpt

BACKGROUND AND PURPOSE: Reported associations between risk of radiation-induced normal tissue injury and single nucleotide polymorphisms (SNPs) in TGFB1, encoding the pro-fibrotic cytokine transforming growth factor-beta 1 (TGF-β1), remain controversial. To overcome publication bias, the international Radiogenomics Consortium collected and analysed individual patient level data from both published and unpublished...

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Identifiers

PMID: 23199655
DOI: 10.1016/j.radonc.2012.10.017
PMCID: PMC3593101

Genes

TGFB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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