Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of TGFbeta1 polymorphisms involved in radiation toxicity with TGFbeta1 secretion in vitro.

Cytokine - 1 Apr 2010

Kim De Ruyck, Laurence Beels, Jan Van Meerbeeck, Wilfried De Neve, Hubert Thierens

Abstract excerpt

TGFbeta1 plasma levels and TGFbeta1 genetic polymorphisms have been linked to radiation-induced lung injury. As the correlation between plasma levels and genotype is not always straightforward, this study investigated the association between TGFbeta1 genotype, considering several polymorphisms, and in vitro TGFbeta1 secretion of human lymphocytes. Four polymorphisms in TGFbeta1 (c.-800, c.-509, c.29, c.74)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Predisposition to Disease
Share to Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Protein Serine-Threonine Kinases

Share to Radiation Injuries

Share to Receptor, Transforming Growth Factor-beta Type I

Share to Receptors, Transforming Growth Factor beta

Share to Transforming Growth Factor beta1

Source

Identifiers

PMID: 20144876
DOI: 10.1016/j.cyto.2009.12.013

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of TGFbeta1 polymorphisms involved in radiation toxicity with TGFbeta1 secretion in vitro.PMID 20144876Read ↗

No effect of the transforming growth factor β1 promoter polymorphism C-509T on TGFB1 gene expression, protein secretion, or cellular radiosensitivity.Semantic proximity Read ↗

A putatively functional haplotype in the gene encoding transforming growth factor beta-1 as a potential biomarker for radiosensitivity.Semantic proximity Read ↗

Individual patient data meta-analysis shows no association between the SNP rs1800469 in TGFB and late radiotherapy toxicity.Semantic proximity Read ↗

No association between TGFB1 polymorphisms and late radiotherapy toxicity: a meta-analysis.Semantic proximity Read ↗

No association between TGF-β1 polymorphisms and radiation-induced lung toxicity in a European cohort of lung cancer patients.Semantic proximity Read ↗

Association of TGF-β1 and XPD polymorphisms with severe acute radiation-induced esophageal toxicity in locally advanced lung cancer patients treated with radiotherapy.Semantic proximity Read ↗

Bioinformatic and functional analysis of TGFBR1 polymorphisms.Semantic proximity Read ↗

A Likely Role for a Novel Cell Therapeutic Target of Transforming Growth Factor-β1 on Radiation Pneumonitis in Lung and Nasopharyngeal Cancer Patients.Semantic proximity Read ↗

TGF-β1 Gene Polymorphisms for Anticipating Radiation-Induced Pneumonitis in Non–Small-Cell Lung Cancer: Different Ethnic AssociationSemantic proximity Read ↗

No association between SNPs regulating TGF-β1 secretion and late radiotherapy toxicity to the breast: results from the RAPPER study.Semantic proximity Read ↗

A study of ethnic differences in TGFβ1 gene polymorphisms and effects on the risk of radiation pneumonitis in non-small-cell lung cancer.Semantic proximity Read ↗

TGF-β1 rs1982073 polymorphism contributes to radiation pneumonitis in lung cancer patients: a meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.