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Article

TGFB1 and TGFBR1 polymorphisms and breast cancer risk in the Nurses' Health Study.

BMC cancer - 11 Sept 2007

Cox David G, Penney Kathryn, Guo Qun, Hankinson Susan E, Hunter David J

Abstract excerpt

BACKGROUND: Transforming growth factor beta 1 (TGFB1) forms a signaling complex with transforming growth factor beta receptors 1 and 2 and has been described as both a tumor suppressor and tumor promoter. Single nucleotide polymorphisms in TGFB1 and a microsatellite in TGFBR1 have been investigated for association with risk of breast cancer, with conflicting results. METHODS: We examined polymorphisms in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17848193
DOI: 10.1186/1471-2407-7-175
PMCID: PMC2082040

Genes

TGFB1
TGFBR1

Provenance

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