A putatively functional haplotype in the gene encoding transforming growth factor beta-1 as a potential biomarker for radiosensitivity.

doi:10.1016/j.ijrobp.2010.08.040

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Article

A putatively functional haplotype in the gene encoding transforming growth factor beta-1 as a potential biomarker for radiosensitivity.

International journal of radiation oncology, biology, physics - 1 Mar 2011

Schirmer Markus A, Brockmöller Jürgen, Rave-Fränk Margret, Virsik Patricia, Wilken Barbara, Kühnle Elna, Campean Radu, Hoffmann Arne O, Müller Katarina, Goetze Robert G, Neumann Michael, Janke Jörg H, Nasser Fatima, Wolff Hendrik A, Ghadimi B Michael, Schmidberger Heinz, Hess Clemens F, Christiansen Hans, Hille Andrea

Abstract excerpt

PURPOSE: To determine whether genetic variability in TGFB1 is related to circulating transforming growth factor-β1 (TGF-β1) plasma concentrations after radiotherapy and to radiosensitivity of lymphoid cells. PATIENTS AND METHODS: Transforming growth factor-β1 plasma concentrations (n=79) were measured in patients 1 year after radiotherapy and chromosomal aberrations (n=71) ex vivo before therapy start....

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Identifiers

PMID: 21183289
DOI: 10.1016/j.ijrobp.2010.08.040

Genes

TGFB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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