Article
Association of a TGF-β1 gene -509 C/T polymorphism with breast cancer risk: a meta-analysis.
Breast cancer research and treatment - 1 Nov 2010
Woo Sang Uk, Park Kyong Hwa, Woo Ok Hee, Yang Dae Sik, Kim Ae-Ree, Lee Eun Sook, Lee Jae-Bok, Kim Yeul Hong, Kim Jun Suk, Seo Jae Hong
Abstract excerpt
Transforming growth factor-β1 (TGF-β1) is negative regulator of cell proliferation and the cell cycle, and plasma levels of TGF-β1 are twice as high in TGF-β1 -509 T homozygotes as in -509 C homozygotes. Published studies on the association between the TGF-β1 gene -509 C/T polymorphism and breast cancer risk are inconclusive, and a meta-analysis is required to verify the association. We performed a meta-analysis...
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