Article
Mining the protein data bank to differentiate error from structural variation in clustered static structures: an examination of HIV protease.
Viruses - 1 Mar 2012
Venkatakrishnan Balasubramanian, Palii Miorel-Lucian, Agbandje-McKenna Mavis, McKenna Robert
Abstract excerpt
The Protein Data Bank (PDB) contains over 71,000 structures. Extensively studied proteins have hundreds of submissions available, including mutations, different complexes, and space groups, allowing for application of data-mining algorithms to analyze an array of static structures and gain insight about a protein's structural variation and possibly its dynamics. This investigation is a case study of HIV protease...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
