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Article

Computational analysis of HIV-1 protease protein binding pockets.

Journal of chemical information and modeling - 25 Oct 2010

Ko Gene M, Reddy A Srinivas, Kumar Sunil, Bailey Barbara A, Garg Rajni

Abstract excerpt

Mutations that arise in HIV-1 protease after exposure to various HIV-1 protease inhibitors have proved to be a difficult aspect in the treatment of HIV. Mutations in the binding pocket of the protease can prevent the protease inhibitor from binding to the protein effectively. In the present study...

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Identifiers

PMID: 20925403
DOI: 10.1021/ci100200u
PMCID: PMC2981608

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20925403-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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