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Article

Analysis of HIV wild-type and mutant structures via in silico docking against diverse ligand libraries.

Journal of chemical information and modeling - 1 Jan 2000

Chang Max W, Lindstrom William, Olson Arthur J, Belew Richard K

Abstract excerpt

The FightAIDS@Home distributed computing project uses AutoDock for an initial virtual screen of HIV protease structures against a broad range of 1771 ligands including both known protease inhibitors and a diverse library of other ligands. The volume of results allows novel large-scale analyses of binding energy "profiles" for HIV structures. Beyond identifying potential lead compounds, these characterizations...

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Identifiers

PMID: 17447753
DOI: 10.1021/ci700044s

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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