Article

Modeling Bias Toward Binding Sites in PDB Structural Models

2024-12-15

Abstract excerpt

The protein data bank (PDB) is one of the richest databases in biology. The structural models deposited have provided insights into protein folds, relationships to evolution, energy functions of structures, and most recently, protein structure prediction, connecting sequence to structure. However, the X-ray crystallography (and cryo-EM) models deposited in the PDB are determined by a combination of refinement algo...

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Literature Corpus work: ca4731ce-77ce-5e02-93c2-a9555e6077a5
DOI: 10.1101/2024.12.14.628518

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