Article
Differential expression of the Gstp2 gene between the aboriginal species Mus spretus and the laboratory mouse Mus musculus.
Mutation research - 30 Aug 2012
Abril Nieves, Ruiz-Laguna Julia, Pueyo Carmen
Abstract excerpt
Glutathione S-transferases (GSTs) are pivotal phase-II enzymes for detoxification of xenobiotics. Pi-class GSTs play key roles in determining cancer susceptibility. The laboratory mouse Mus musculus (Mm) has two GST-Pi-encoding genes; while MmGstp1 is the counterpart of the unique human and rat Pi-class GST gene, the function of MmGstp2 remains unclear because its expression is almost undetectable in liver and...
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