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Article

Polymorphic electrophile response elements in the mouse glutathione S-transferase GSTa1 gene that confer increased induction.

Cancer letters - 26 Mar 2001

Zhu M, Chapman W G, Oberley M J, Wasserman W W, Fahl W E

Abstract excerpt

Induced transcription of a battery of stress response genes in mammals, including several phase I and phase II drug-metabolizing enzymes, is regulated by the electrophile responsive element (EpRE). Because previous directed mutagenesis of nucleotide motifs within the large, composite EpRE were shown to affect transcription factor binding and associated induced expression of dependent genes, we hypothesized that...

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PMID: 11179824
DOI: 10.1016/s0304-3835(00)00664-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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