Structure and in vitro transcription of the rat CYP2A1 and CYP2A2 genes and regional localization of the CYP2A gene subfamily on mouse chromosome 7.

doi:10.1021/bi00457a032

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Article

Structure and in vitro transcription of the rat CYP2A1 and CYP2A2 genes and regional localization of the CYP2A gene subfamily on mouse chromosome 7.

Biochemistry - 6 Feb 1990

Matsunaga T, Nomoto M, Kozak C A, Gonzalez F J

Abstract excerpt

The CYP2A1 and CYP2A2 genes code for hepatic steroid hydroxylases and differ in their development regulation and expression in male and female rats. In order to explore the mechanism of regulation of these two genes, both genes were isolated and sequenced, their upstream regions compared, and the...

Topics

Amino Acid Sequence
Animals
Base Sequence
Chromosome Mapping
Crosses, Genetic
Female
Gene Expression Regulation
Genetic Linkage
In Vitro Techniques
Male
Mice
Molecular Sequence Data
Multigene Family
Mutation
Promoter Regions, Genetic
Rats
Steroid Hydroxylases
Transcription, Genetic

Source

Open in PubMed

Identifiers

PMID: 2322568
DOI: 10.1021/bi00457a032

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2322568-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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