Article
Enhancer elements in the mouse CYP1A2 gene: a comparative sequencing among different inbred mouse strains.
Mutation research - 15 Aug 2007
Mikhailova Olga N, Gulyaeva Lyudmila F, Filipenko Maxim L, Kaledin Vasily I
Abstract excerpt
CYP1A2 expression is constitutively high in mouse liver and is well known for metabolizing several drugs and many procarcinogens to reactive intermediates that can cause toxicity or cancer. In the present study, the basal level of hepatic CYP1A2 activity was shown to vary among different inbred m...
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