Article
Determining differentially expressed miRNAs and validating miRNA--target relationships using the SPRET/Ei mouse strain.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Feb 2015
Timmermans S, Van Hauwermeiren F, Puimège L, Dejager L, Van Wonterghem E, Vanhooren V, Mestdagh P, Libert C, Vandenbroucke R E
Abstract excerpt
Micro RNAs (miRs) are involved in many biological processes. The challenge of identifying genes influenced by miRs is evidenced by the relatively few validated miR-target interactions. In this work, we used the Mus spretus SPRET/Ei strain as an in vivo system to identify new miR-target relations. Mus spretus diverged from Mus musculus over one million years ago, making it genetically and phenotypically divergent....
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