Article
Pi-class glutathione S-transferase: regulation and function.
Chemico-biological interactions - 24 Apr 1998
Henderson C J, McLaren A W, Moffat G J, Bacon E J, Wolf C R
Abstract excerpt
Our laboratory has been involved in the study of Glutathione S-transferase pi (GST pi) for many years, both in terms of regulation of gene expression and in trying to understand the endogenous function(s) of this enzyme and also what role it may play in the carcinogenic process [1]. Over-expressi...
Topics
- Alleles
- Animals
- Base Sequence
- Binding Sites
- DNA
- Female
- Gene Expression Regulation, Enzymologic
- Glutathione S-Transferase pi
- Glutathione Transferase
- Humans
- Isoenzymes
- Male
- Mice
- Mice, Knockout
- Models, Biological
- Phenotype
- Promoter Regions, Genetic
- RNA, Messenger
