Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tumor necrosis factor gene variation predicts hippocampus volume in healthy individuals.

Biological psychiatry - 15 Oct 2012

Baune Bernhard T, Konrad Carsten, Grotegerd Dominik, Suslow Thomas, Ohrmann Patricia, Bauer Jochen, Arolt Volker, Heindel Walter, Domschke Katharina, Schöning Sonja, Rauch Astrid Veronika, Sehlmeyer Christina, Kugel Harald, Dannlowski Udo

Abstract excerpt

BACKGROUND: Cytokines such as tumor necrosis factor (TNF) α have been implicated in neurodegeneration relevant to various neuropsychiatric disorders. Little is known about the genetic predisposition to neurodegenerative properties of cytokine genes on brain function and on hippocampus (HC) function in particular. In this study we investigate the neurodegenerative role of TNF polymorphisms on brain morphology in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Aged

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hippocampus

Share to Image Processing, Computer-Assisted

Share to Magnetic Resonance Imaging

Share to Polymorphism, Single Nucleotide

Share to Tumor Necrosis Factor-alpha

Share to Young Adult

Source

Identifiers

PMID: 22554453
DOI: 10.1016/j.biopsych.2012.04.002

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tumor necrosis factor gene variation predicts hippocampus volume in healthy individuals.PMID 22554453Read ↗

TNF receptors 1 and 2 exert distinct region-specific effects on striatal and hippocampal grey matter volumes (VBM) in healthy adults.Semantic proximity Read ↗

Interleukin-6 gene (IL-6): a possible role in brain morphology in the healthy adult brain.Semantic proximity Read ↗

Influence of vascular endothelial growth factor variation on human hippocampus morphology.Semantic proximity Read ↗

Effects of tumor necrosis factor-α polymorphism on the brain structural changes of the patients with major depressive disorderSemantic proximity Read ↗

Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes.Semantic proximity Read ↗

BDNF Val66Met allele is associated with reduced hippocampal volume in healthy subjects.Semantic proximity Read ↗

A GWAS-Derived Polygenic Score for Interleukin-1β is Associated with Hippocampal Volume in Two SamplesSemantic proximity Read ↗

Brain scans from 21297 individuals reveal the genetic architecture of hippocampal subfield volumesSemantic proximity Read ↗

Reduced hippocampal volumes in healthy carriers of brain-derived neurotrophic factor Val66Met polymorphism: meta-analysis.Semantic proximity Read ↗

Relationship between Interleukin-6 gene polymorphism and hippocampal volume in antipsychotic-naïve schizophrenia: evidence for differential susceptibility?Semantic proximity Read ↗

Genetic, psychosocial and clinical factors associated with hippocampal volume in the general population.Semantic proximity Read ↗

Impact of genetic variants on hippocampal volume among individuals with schizophrenia and bipolar disorders.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.