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Article

Influence of vascular endothelial growth factor variation on human hippocampus morphology.

Biological psychiatry - 15 Nov 2008

Blumberg Hilary P, Wang Fei, Chepenik Lara G, Kalmar Jessica H, Edmiston Elliot Kale, Duman Ronald S, Gelernter Joel

Abstract excerpt

BACKGROUND: Morphological abnormalities in hippocampus have been implicated in neuropsychiatric disorders, including depression, schizophrenia, and dementia. Vascular endothelial growth factor (VEGF) has been demonstrated to have neurogenic effects in the hippocampus in rats. However, influence of VEGF variation on hippocampus morphology in humans has yet to be shown. Here, an integrated genetic and neuroimaging...

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Identifiers

PMID: 18707678
DOI: 10.1016/j.biopsych.2008.07.003
PMCID: PMC2649728

Genes

VEGFA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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