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Article

Interleukin-6 gene (IL-6): a possible role in brain morphology in the healthy adult brain.

Journal of neuroinflammation - 6 Jul 2012

Baune Bernhard T, Konrad Carsten, Grotegerd Dominik, Suslow Thomas, Birosova Eva, Ohrmann Patricia, Bauer Jochen, Arolt Volker, Heindel Walter, Domschke Katharina, Schöning Sonja, Rauch Astrid V, Uhlmann Christina, Kugel Harald, Dannlowski Udo

Abstract excerpt

BACKGROUND: Cytokines such as interleukin 6 (IL-6) have been implicated in dual functions in neuropsychiatric disorders. Little is known about the genetic predisposition to neurodegenerative and neuroproliferative properties of cytokine genes. In this study the potential dual role of several IL-6 polymorphisms in brain morphology is investigated. METHODOLOGY: In a large sample of healthy individuals (N = 303),...

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Identifiers

PMID: 22695063
DOI: 10.1186/1742-2094-9-125
PMCID: PMC3464888

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