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Article

BDNF Val66Met allele is associated with reduced hippocampal volume in healthy subjects.

Biological psychiatry - 1 May 2006

Bueller Joshua A, Aftab Macksood, Sen Srijan, Gomez-Hassan Diana, Burmeister Margit, Zubieta Jon-Kar

Abstract excerpt

BACKGROUND: A frequent polymorphism of the brain-derived neurotrophic factor (BDNF) gene (val(66)met) has been suggested to modulate hippocampal neuronal plasticity and has been associated with individual variations in emotional reactivity traits and episodic memory. METHODS: The hippocampal formation was outlined in high-resolution anatomical magnetic resonance imaging (MRI) data in a sample of 36 healthy...

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Source

Identifiers

PMID: 16442082
DOI: 10.1016/j.biopsych.2005.09.022

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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