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Article

Mitochondrial tRNA mutations are associated with maternally inherited hypertension in two Han Chinese pedigrees.

Human mutation - 1 Aug 2012

Qiu Qiaomeng, Li Ronghua, Jiang Pingping, Xue Ling, Lu Yang, Song Yaman, Han Jungang, Lu Zhongqiu, Zhi Shaoce, Mo Jun Qin, Guan Min-Xin

Abstract excerpt

We report here the clinical, genetic, molecular, and biochemical evaluations in two Han Chinese families with maternally inherited hypertension. Fourteen of 20 adult matrilineal relatives of these families exhibited a wide range of severity in hypertension, while none of offspring of affected fathers had hypertension. The age-at-onset of hypertension in matrilineal relatives varied from 37 years to 83 years, with...

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Identifiers

PMID: 22549939
DOI: 10.1002/humu.22109

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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