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[Mutations in mitochondrial DNA associated with hypertension].

Yi chuan = Hereditas - 1 Sept 2011

Xue Ling, Chen Hong, Meng Yan-Zi, Wang Yan, Lu Zhong-Qiu, Lu Jian-Xin, Guan Min-Xin

Abstract excerpt

Mutations in mitochondrial DNA (mtDNA) are one of the molecular bases of hypertension. Among these, the tRNAMet A4435G, tRNAMet/tRNAGln A4401G, tRNAIle A4263G, T4291C and A4295G mutations have been reported to be associated with essential hypertension. These mutations alter the structure of the corresponding mitochondrial tRNAs and cause failures in tRNA metabolism. These shortages of these tRNAs lead to an...

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Identifiers

PMID: 21951790
DOI: 10.3724/sp.j.1005.2011.00911

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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