Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[The mitochondrial tRNAMet/tRNAGlnA4401G and tRNACysG5821A mutations may be associated with hypertension in two Han Chinese families].

Yi chuan = Hereditas - 1 Feb 2014

Xu Meifen, He Yiqun, Geng Junwei, Meng Yanzi, Yu Han, Lin Zhi, Shi Suxue, Xue Ling, Lu Zhongqiu, Guan Minxin

Abstract excerpt

Mitochondrial tRNA genes are the hot spots for mutations associated with essential hypertension. We report here the clinical and molecular genetic characterization of two Han Chinese pedigrees with materially inherited essential hypertension. Clinical evaluation revealed the variable severity and age-at-onset of hypertension among matrilineal relatives. In particular, the age-at-onset of hypertension in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to Ethnicity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hypertension

Share to Mitochondria

Share to Pedigree

Share to RNA, Transfer, Amino Acid-Specific

Share to RNA, Transfer, Gln

Share to RNA, Transfer, Met

Source

Identifiers

PMID: 24846941
DOI: 10.3724/sp.j.1005.2014.00127

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[The mitochondrial tRNAMet/tRNAGlnA4401G and tRNACysG5821A mutations may be associated with hypertension in two Han Chinese families].PMID 24846941Read ↗

The Mitochondrial tRNAAsp T7561C, tRNAHis C12153T, and A12172G Mutations May Be Associated with Essential Hypertension in a Han Chinese Pedigree.Semantic proximity Read ↗

Mitochondrial tRNAAla C5601T mutation may modulate the clinical expression of tRNAMet A4435G mutation in a Han Chinese family with hypertension.Semantic proximity Read ↗

Molecular characterization of a Chinese family carrying a novel C4329A mutation in mitochondrial tRNAIle and tRNAGln genes.Semantic proximity Read ↗

The tRNAMet 4435A>G mutation in the mitochondrial haplogroup G2a1 is responsible for maternally inherited hypertension in a Chinese pedigree.Semantic proximity Read ↗

Molecular characterization of a pedigree carrying the hypertension‑associated mitochondrial tRNAGln T4363C mutation.Semantic proximity Read ↗

[Mutations in mitochondrial DNA associated with hypertension].Semantic proximity Read ↗

Mitochondrial tRNAThr 15909A>G mutation associated with hypertension in a Chinese Han pedigree.Semantic proximity Read ↗

Molecular characterization of two Chinese pedigrees with maternally inherited hypertension.Semantic proximity Read ↗

The role of mitochondrial genome in essential hypertension in a Chinese Han population.Semantic proximity Read ↗

Mitochondrial tRNA mutations in 2070 Chinese Han subjects with hypertension.Semantic proximity Read ↗

Maternally inherited hypertension is associated with the mitochondrial tRNA(Ile) A4295G mutation in a Chinese family.Semantic proximity Read ↗

Mitochondrial tRNASer(UCN) 7471delC may be a novel mutation associated with maternally transmitted hypertension.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.