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Mitochondrial tRNA mutations in 2070 Chinese Han subjects with hypertension.

Mitochondrion - 1 Sept 2016

Xue Ling, Wang Meng, Li Haiying, Wang Heng, Jiang Feng, Hou Lingling, Geng Junwei, Lin Zhi, Peng Yanyan, Zhou Hong, Yu Han, Jiang Pingping, Mo Jun Qin, Guan Min-Xin

Abstract excerpt

BACKGROUND: Mitochondria have the profound impact on vascular function in both health and disease. However, mitochondrial genetic determinants for the development of hypertension remain poorly explored. METHODS AND RESULTS: The Sanger sequence analysis of 22 mitochondrial tRNA genes were performed in a cohort of 2070 Han Chinese hypertensive and 512 control subjects. This analysis identified 165 variants among 22...

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PMID: 27544295
DOI: 10.1016/j.mito.2016.08.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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