Article
Mitochondrial tRNAMet mutation is associated with clinical and biochemical characteristics in primary hypertension.
Molecular medicine reports - 1 Jun 2013
Lu Chang-Qing, Zhang Jin-Ying, Xu Ai-Guo, Zhang Juang-Juang, Li Dan-Dan, Fu Xin, Guo Jing, Xu Qin-Fu
Abstract excerpt
Mitochondrial DNA mutations have been increasingly associated with various diseases. An association between the mitochondrial tRNA gene mutation, tRNAMet, and primary hypertension has been suggested. In the present study, the association between the tRNAMet mutation and the development of primary hypertension was investigated by assessing clinical and biological indicators in 800 patients with primary...
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