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Article

Molecular characterization of two Chinese pedigrees with maternally inherited hypertension.

The journal of gene medicine - 1 Apr 2021

Ding Yu, Yu Jinfang, Guo Qinxian, Gao Beibei, Huang Jinyu

Abstract excerpt

BACKGROUND: Mutations in mitochondrial tRNA (mt-tRNA) genes are associated with hypertension, although their pathogenic mechanisms remain poorly understood. METHODS: In the present study, two Han Chinese families with maternally transmitted hypertension were interviewed. The mtDNA mutations of matrilineal relatives were screened by polymerase chain reaction-Sanger sequencing. Mitochondrial ATP, membrane potential...

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PMID: 33625761
DOI: 10.1002/jgm.3328

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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