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Article

The 5-HTTLPR polymorphism is associated with altered hemodynamic responses during appetitive conditioning.

Human brain mapping - 1 Oct 2013

Klucken Tim, Wehrum Sina, Schweckendiek Jan, Merz Christian Josef, Hennig Juergen, Vaitl Dieter, Stark Rudolf

Abstract excerpt

BACKGROUND: Current models suggest that a variation in the promoter region of the serotonin transporter gene (5-HTTLPR) is associated with altered amygdala reactivity not only towards negative but also towards positive stimuli, which has been neglected in the past. This association may possibly convey an elevated vulnerability for psychopathology like abuse, craving, and relapses. Since appetitive conditioning is...

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Identifiers

PMID: 22505321
DOI: 10.1002/hbm.22085
PMCID: PMC6870347

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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