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Article

Affective neural responses modulated by serotonin transporter genotype in clinical anxiety and depression.

PloS one - 1 Jan 2015

Oathes Desmond J, Hilt Lori M, Nitschke Jack B

Abstract excerpt

Serotonin transporter gene variants are known to interact with stressful life experiences to increase chances of developing affective symptoms, and these same variants have been shown to influence amygdala reactivity to affective stimuli in non-psychiatric populations. The impact of these gene variants on affective neurocircuitry in anxiety and mood disorders has been studied less extensively. Utilizing a...

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Identifiers

PMID: 25675343
DOI: 10.1371/journal.pone.0115820
PMCID: PMC4344476

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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