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Article

Serotonin Transporter Gene Polymorphism Modulates Activity and Connectivity within an Emotional Arousal Network of Healthy Men during an Aversive Visceral Stimulus.

PloS one - 1 Jan 2015

Kilpatrick Lisa A, Mayer Emeran A, Labus Jennifer S, Gupta Arpana, Hamaguchi Toyohiro, Mizuno Tomoko, Komuro Hazuki, Kano Michiko, Kanazawa Motoyori, Aoki Masashi, Fukudo Shin

Abstract excerpt

BACKGROUND AND AIMS: The 5-hydroxytryptamine transporter gene-linked polymorphic region (5-HTTLPR) has been linked to increased stress responsiveness and negative emotional states. During fearful face recognition individuals with the s allele of 5-HTTLPR show greater amygdala activation. We aimed to test the hypothesis that the 5-HTTLPR polymorphism differentially affects connectivity within brain networks during...

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Identifiers

PMID: 25893242
DOI: 10.1371/journal.pone.0123183
PMCID: PMC4404144

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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