Article
Individual differences in neural correlates of fear conditioning as a function of 5-HTTLPR and stressful life events.
Social cognitive and affective neuroscience - 1 Mar 2013
Klucken Tim, Alexander Nina, Schweckendiek Jan, Merz Christian J, Kagerer Sabine, Osinsky Roman, Walter Bertram, Vaitl Dieter, Hennig Juergen, Stark Rudolf
Abstract excerpt
Fear learning is a crucial process in the pathogeneses of psychiatric disorders, which highlights the need to identify specific factors contributing to interindividual variation. We hypothesized variation in the serotonin transporter gene (5-HTTLPR) and stressful life events (SLEs) to be associated with neural correlates of fear conditioning in a sample of healthy male adults (n = 47). Subjects were exposed to a...
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