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Article

Functional gene polymorphisms in the serotonin system and traumatic life events modulate the neural basis of fear acquisition and extinction.

PloS one - 1 Jan 2012

Hermann Andrea, Küpper Yvonne, Schmitz Anja, Walter Bertram, Vaitl Dieter, Hennig Jürgen, Stark Rudolf, Tabbert Katharina

Abstract excerpt

Fear acquisition and extinction are crucial mechanisms in the etiology and maintenance of anxiety disorders. Moreover, they might play a pivotal role in conveying the influence of genetic and environmental factors on the development of a (more or less) stronger proneness for, or resilience against psychopathology. There are only few insights in the neurobiology of genetically and environmentally based individual...

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Identifiers

PMID: 22957066
DOI: 10.1371/journal.pone.0044352
PMCID: PMC3434167

Genes

TPH2

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