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Article

The N-terminal region of the human 5-HT₂C receptor has as a cleavable signal peptide.

European journal of pharmacology - 5 Jun 2012

Jahnsen Jan Anker, Uhlén Staffan

Abstract excerpt

The 5-hydroxytryptamine 2C (5-HT(2C)) receptor has a single nucleotide polymorphism (SNP) site at amino acid position 23 in its N-terminal tail. The polymorphism involves conversion of a cysteine to serine. The site, designated C23S, is located within a 32 amino acid long predicted signal peptide. The aim of the present study was to investigate whether the 5-HT(2C) receptor indeed has a functional cleavable...

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Source

Identifiers

PMID: 22497996
DOI: 10.1016/j.ejphar.2012.03.043

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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