Article
Pharmacological properties of the Cys23Ser single nucleotide polymorphism in human 5-HT2C receptor isoforms.
The pharmacogenomics journal - 1 Jan 2005
Fentress H M, Grinde E, Mazurkiewicz J E, Backstrom J R, Herrick-Davis K, Sanders-Bush E
Abstract excerpt
The human serotonin 2C (5-HT2C) receptor undergoes extensive RNA editing, generating multiple isoforms; the most prominent isoform in the human brain is the extensively edited VSV isoform. In addition, a naturally occurring single nucleotide polymorphism (SNP) is found in the coding region of the...
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