A single nucleotide polymorphism in the human serotonin transporter introduces a new site for N-linked glycosylation.

doi:10.1016/j.neuropharm.2009.05.009

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Article

A single nucleotide polymorphism in the human serotonin transporter introduces a new site for N-linked glycosylation.

Neuropharmacology - 1 Sept 2009

Rasmussen Trine N, Plenge Per, Bay Tina, Egebjerg Jan, Gether Ulrik

Abstract excerpt

The human serotonin transporter (hSERT) is responsible for reuptake of serotonin (5-HT) from the synaptic cleft and is target for antidepressant medicine. Differential hSERT activity caused by genetic polymorphisms is believed to affect the risk of developing depression and, moreover, to affect the response to antidepressant therapy. The hSERT contains in the second extracellular loop (EL2) two sites for N-linked...

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PMID: 19500602
DOI: 10.1016/j.neuropharm.2009.05.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.