Article
[Association of hOGG1 genotype with life style and oxidative DNA damage in five ethnic populations in China].
Wei sheng yan jiu = Journal of hygiene research - 1 Jan 2012
Wu Shuang, Jiang Yousheng, Yuan Jianhui, Zhuang Zhixiong, Ke Yuebin
Abstract excerpt
OBJECTIVE: To assess the natural variation of hOGG1 gene and the gene-environmental interactions. METHODS: The hOGG1 codon 326 polymorphism and urinary 8-OHdG levels were investigated in a large sample of healthy individuals (n = 953) from five ethnic populations in China by using PCR-RFLP and HPLC-ECD. Life style parameters were obtained through a questionnaire survey. RESULTS: The allelic frequencies of hOGG1...
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