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The joint effect of smoking and hOGG1 genotype on oral cancer in Taiwan.

Anticancer research - 1 Sept 2012

Tsai Chia-Wen, Tsai Ming-Hsui, Tsou Yung-An, Shih Liang-Chun, Tseng Hsien-Chang, Chang Wen-Shin, Ho Chien-Yi, Lee Hong-Zin, Bau Da-Tian

Abstract excerpt

This study aimed at evaluating the association and interaction among human 8-oxoguanine DNA N-glycosylase 1 (hOGG1) genotypic polymorphism, smoking status and oral cancer risk in Taiwan. For this purpose, the well-known polymorphic variants of hOGG1, codon 326, was analyzed for its association with oral cancer susceptibility, and its joint effect with individual smoking habits on oral cancer susceptibility. In...

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PMID: 22993322

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