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Article

Polymorphic variation in hOGG1 and risk of cancer: a review of the functional and epidemiologic literature.

Molecular carcinogenesis - 1 Mar 2005

Weiss J M, Goode E L, Ladiges W C, Ulrich Cornelia M

Abstract excerpt

The gene encoding human 8-oxoguanine glycosylase 1 (hOGG1) is involved in DNA base excision repair. The encoded DNA glycosylase excises 7,8-dihydro-8-oxoguanine (8-OHdG), a highly mutagenic base produced in DNA as a result of exposure to reactive oxygen species (ROS). Polymorphisms in this gene may alter glycosylase function and an individual's ability to repair damaged DNA, possibly resulting in genetic...

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Identifiers

PMID: 15584022
DOI: 10.1002/mc.20067

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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