Article
The effect of hOGG1 Ser326Cys polymorphism on cancer risk: evidence from a meta-analysis.
PloS one - 1 Jan 2011
Wei Bingbing, Zhou You, Xu Zhuoqun, Xi Bo, Cheng Huan, Ruan Jun, Zhu Ming, Hu Qiang, Wang Qiang, Wang Zhirong, Yan Zhiqiang, Jin Ke, Zhou Deqi, Xuan Feng, Huang Xing, Shao Jianfeng, Lu Peng
Abstract excerpt
BACKGROUND: Human oxoguanine glycosylase 1 (hOGG1) in base excision repair (BER) pathway plays a vital role in DNA repair. Numerous epidemiological studies have evaluated the association between hOGG1 Ser326Cys polymorphism and the risk of cancer. However, the results of these studies on the association remain conflicting. To derive a more precise estimation of the association, we conducted a meta-analysis....
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