Article
Contribution of HOGG1 Ser³²⁶Cys polymorphism to the development of prostate cancer in smokers: meta-analysis of 2779 cases and 3484 controls.
PloS one - 1 Jan 2012
Xu Bin, Tong Na, Chen Shu-Qiu, Yang Yu, Zhang Xiao-Wen, Liu Jin, Hu Xiang-Nong, Sha Guo-Zhu, Chen Ming
Abstract excerpt
The HOGG1 gene catalyzes the excision of modified bases and removal of DNA damage adducts. It may play an important role in the prevention of carcinogenesis. Ser³²⁶Cys polymorphism localizes in exon 7 of the hOGG1 gene. It takes the form of an amino acid substitution, from serine to cysteine, in...
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