Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Head and neck cancer: genetic polymorphisms and folate metabolism.

Brazilian journal of otorhinolaryngology - 1 Feb 2012

Galbiatti Ana Lívia Silva, Ruiz Mariangela Torreglosa, Maniglia José Victor, Raposo Luis Sérgio, Pavarino-Bertelli Erika Cristina, Goloni-Bertollo Eny Maria

Abstract excerpt

UNLABELLED: Epidemiological evidence suggests that genetic variants encoding enzymes involved in folate metabolism may modulate HNSCC risk by altering DNA methylation synthesis and genomic estability. AIM: A review of the literature on genetic polymorphisms involved in folate metabolism and risk of head and neck cancer was carried out. METHODOLOGY: An electronic search was made on the Medline database to select...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Methylation
Share to Folic Acid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to MTHFD1 gene

Share to MTRR gene

Share to RFC1 gene

Share to Genotype

Share to Head and Neck Neoplasms

Share to Polymorphism, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 22392251
DOI: 10.1590/s1808-86942012000100021
PMCID: PMC9443880

Genes

MTHFR
MTHFD1
MTR
MTRR
RFC1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Head and neck cancer: genetic polymorphisms and folate metabolism.PMID 22392251Read ↗

Association between 11 genetic polymorphisms in folate-metabolising genes and head and neck cancer risk.Semantic proximity Read ↗

Polymorphisms and haplotypes in methylenetetrahydrofolate reductase gene and head and neck squamous cell carcinoma risk.Semantic proximity Read ↗

Polymorphism of methylenetetrahydrofolate reductase (MTHFR) gene and risk of head and neck squamous cell carcinoma.Semantic proximity Read ↗

5-Methyltetrahydrofolate-homocysteine methyltransferase gene polymorphism (MTR) and risk of head and neck cancer.Semantic proximity Read ↗

Polymorphisms of methionine synthase and methionine synthase reductase and risk of squamous cell carcinoma of the head and neck: a case-control analysis.Semantic proximity Read ↗

MTHFD1 G1958A, BHMT G742A, TC2 C776G and TC2 A67G polymorphisms and head and neck squamous cell carcinoma risk.Semantic proximity Read ↗

DNMT3B C46359T and SHMT1 C1420T polymorphisms in the folate pathway in carcinogenesis of head and neck.Semantic proximity Read ↗

Polymorphic variants of folate metabolism genes and the risk of laryngeal cancer.Semantic proximity Read ↗

Gene Polymorphisms Involved in Folate Metabolism and DNA Methylation with the Risk of Head and Neck Cancer.Semantic proximity Read ↗

MTHFR C677T gene polymorphism and head and neck cancer risk: a meta-analysis based on 23 publications.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase polymorphisms and risk of squamous cell carcinoma of the head and neck: a case-control analysis.Semantic proximity Read ↗

MTHFR C677T and A1298C polymorphisms as predictors of radiotherapy response in head and neck squamous cell carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.