Article
Polymorphic variants of folate metabolism genes and the risk of laryngeal cancer.
Molecular biology reports - 1 Jan 2010
Kruszyna Łukasz, Lianeri Margarita, Rydzanicz Małgorzata, Gajecka Marzena, Szyfter Krzysztof, Jagodziński Paweł P
Abstract excerpt
Carcinogenesis may result from abnormal methylation of cancer-related genes regulatory sequence. Though, the polymorphic variants of genes encoding enzymes of folate and methionine metabolism may have an effect on DNA methylation. Using PCR-RFLPs, we examined the polymorphism distribution of gene...
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