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Article

Interpretation of genome-wide infinium methylation data from ligated DNA in formalin-fixed, paraffin-embedded paired tumor and normal tissue.

BMC research notes - 22 Feb 2012

Jasmine Farzana, Rahaman Ronald, Roy Shantanu, Raza Maruf, Paul Rupash, Rakibuz-Zaman Muhammad, Paul-Brutus Rachelle, Dodsworth Charlotte, Kamal Mohammed, Ahsan Habibul, Kibriya Muhammad G

Abstract excerpt

BACKGROUND: Formalin-fixed, paraffin-embedded (FFPE) samples are a highly desirable resource for epigenetic studies, but there is no suitable platform to assay genome-wide methylation in these widely available resources. Recently, Thirlwell et al. (2010) have reported a modified ligation-based DNA repair protocol to prepare FFPE DNA for the Infinium methylation assay. In this study, we have tested the accuracy of...

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Identifiers

PMID: 22357164
DOI: 10.1186/1756-0500-5-117
PMCID: PMC3309956

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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