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Article

Targeted or whole genome sequencing of formalin fixed tissue samples: potential applications in cancer genomics.

Oncotarget - 22 Sept 2015

Munchel Sarah, Hoang Yen, Zhao Yue, Cottrell Joseph, Klotzle Brandy, Godwin Andrew K, Koestler Devin, Beyerlein Peter, Fan Jian-Bing, Bibikova Marina, Chien Jeremy

Abstract excerpt

Current genomic studies are limited by the poor availability of fresh-frozen tissue samples. Although formalin-fixed diagnostic samples are in abundance, they are seldom used in current genomic studies because of the concern of formalin-fixation artifacts. Better characterization of these artifacts will allow the use of archived clinical specimens in translational and clinical research studies. To provide a...

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Identifiers

PMID: 26305677
DOI: 10.18632/oncotarget.4671
PMCID: PMC4694877

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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