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Genome‐wide DNA methylation analysis of formalin‐fixed paraffin embedded colorectal cancer tissue

28 Mar 2014

Abstract excerpt

Formalin fixation and embedding of clinical tissue samples in paraffin is a common method for archiving biological material. These samples are often well annotated and provide an invaluable resource for research. However, this process of fixation and storage of tissue leads to DNA damage and fragmentation. The use of DNA from formalin fixed, paraffin-embedded (FFPE) tissue to interrogate methylation levels on a...

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Share to Epigenetics and DNA Methylation
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PMID: 24677610
DOI: 10.1002/gcc.22164

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